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Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

To understand drug combination effect, it is necessary to decipher the interactions between drug targets—many of which are signaling molecules. Previously, such signaling pathway models are largely based on the compilation of literature data from heterogeneous cellular contexts. Indeed, de novo reco...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bansal, Mukesh, He, Jing, Peyton, Michael, Kustagi, Manjunath, Iyer, Archana, Comb, Michael, White, Michael, Minna, John D., Califano, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322741/
https://ncbi.nlm.nih.gov/pubmed/30615629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208646
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