Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

Cooperation of multiple mutations is thought to be required for cancer development. In previous studies, murine myeloid leukemias induced by transducing wild-type bone marrow progenitors with a SRY sex determining region Y-box 4 (Sox4)–expressing retrovirus frequently carried proviral insertions at...

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Detalhes bibliográficos
Main Authors: Aue, Georg, Du, Yang, Cleveland, Susan M., Smith, Stephen B., Davé, Utpal P., Liu, Delong, Weniger, Marc A., Metais, Jean Yves, Jenkins, Nancy A., Copeland, Neal G., Dunbar, Cynthia E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208283/
https://ncbi.nlm.nih.gov/pubmed/21878674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-351528
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