A role for proapoptotic Bax and Bak in T-cell differentiation and transformation

Proapoptotic Bax and Bak are the key B-cell lymphoma-2 family members mediating apoptosis through the intrinsic pathway. Cells doubly deficient for Bax and Bak are profoundly resistant to apoptotic stimuli originating from multiple stimuli. Here we describe mice in which Bax and Bak have been delete...

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Bibliografiske detaljer
Main Authors: Biswas, Subhrajit, Shi, Qiong, Matise, Lauren, Cleveland, Susan, Dave, Utpal, Zinkel, Sandra
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012541/
https://ncbi.nlm.nih.gov/pubmed/20813900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279687
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