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Tgif1 Regulates Quiescence and Self-Renewal of Hematopoietic Stem Cells

TG-interacting factor 1 (TGIF1) is a transcriptional repressor that can modulate retinoic acid and transforming growth factor β signaling pathways. It is required for myeloid progenitor cell differentiation and survival, and mutations in the TGIF1 gene cause holoprosencephaly. Furthermore, we have p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yan, Ling, Womack, Bethany, Wotton, David, Guo, Yan, Shyr, Yu, Davé, Utpal, Li, Chun, Hiebert, Scott, Brandt, Stephen, Hamid, Rizwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889555/
https://ncbi.nlm.nih.gov/pubmed/24100014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01076-13
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