AAV Joins the Rank of Genotoxic Vectors

par Davé, Utpal P., Cornetta, Kenneth
Publié dans Mol Ther (2021)

Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia

par Yan, Ling, Davé, Utpal P., Engel, Michael, Brandt, Stephen J., Hamid, Rizwan
Publié dans J Cell Mol Med (2020)

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease

par Ye, Jin, Davé, Utpal P., Grishin, Nick V., Goldstein, Joseph L., Brown, Michael S.
Publié 2000

LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding

par Layer, Justin H., Alford, Catherine E., McDonald, W. Hayes, Davé, Utpal P.
Publié dans Mol Cell Biol (2016)

LDB1 Enforces Stability on Direct and Indirect Oncoprotein Partners in Leukemia

par Layer, Justin H., Christy, Michael, Placek, Lindsey, Unutmaz, Derya, Guo, Yan, Davé, Utpal P.
Publié dans Mol Cell Biol (2020)

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

par Elliott, Natalina E., Cleveland, Susan M., Grann, Victor, Janik, John, Waldmann, Thomas A., Davé, Utpal P.
Publié 2011

Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias

par Goodings, Charnise, Tripathi, Rati, Cleveland, Susan M., Elliott, Natalina, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publié dans Leuk Res (2014)

LIM domain only-2 (Lmo2) induces T-cell leukemia with epigenetic deregulation of CD4

par Cleveland, Susan M., Goodings, Charnise, Tripathi, Rati M., Elliott, Natalina, Thompson, Mary Ann, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publié dans Exp Hematol (2014)

Murine Leukemias with Retroviral Insertions at Lmo2 Are Predictive of the Leukemias Induced in SCID-X1 Patients Following Retroviral Gene Therapy

par Davé, Utpal P., Akagi, Keiko, Tripathi, Rati, Cleveland, Susan M., Thompson, Mary A., Yi, Ming, Stephens, Robert, Downing, James R., Jenkins, Nancy A., Copeland, Neal G.
Publié 2009

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

par Aue, Georg, Du, Yang, Cleveland, Susan M., Smith, Stephen B., Davé, Utpal P., Liu, Delong, Weniger, Marc A., Metais, Jean Yves, Jenkins, Nancy A., Copeland, Neal G., Dunbar, Cynthia E.
Publié 2011

Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation

par Goodings, Charnise, Smith, Elizabeth, Mathias, Elizabeth, Elliott, Natalina, Cleveland, Susan M., Tripathi, Rati M., Layer, Justin H., Chen, Xi, Guo, Yan, Shyr, Yu, Hamid, Rizwan, Du, Yang, Davé, Utpal P.
Publié dans Stem Cells (2015)

Lmo2 induces hematopoietic stem cell like features in T-cell progenitor cells prior to leukemia

par Cleveland, Susan M., Smith, Stephen, Tripathi, Rati, Mathias, Elizabeth M., Goodings, Charnise, Elliott, Natalina, Peng, Dunfa, El-Rifai, Wael, Yi, Dajun, Chen, Xi, Li, Liqi, Mullighan, Charles, Downing, James R., Love, Paul, Davé, Utpal P.
Publié 2013

Ldb1 is required for Lmo2 oncogene–induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia

par Li, LiQi, Mitra, Apratim, Cui, Kairong, Zhao, Bin, Choi, Seeyoung, Lee, Jan Y., Stamos, Daniel B., El-Khoury, Dalal, Warzecha, Claude, Pfeifer, Karl, Hardwick, Joyce, Zhao, Keji, Venters, Bryan, Davé, Utpal P., Love, Paul E.
Publié dans Blood (2020)

Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted Therapies

par Greenplate, Allison, Wang, Kai, Tripathi, Rati M., Palma, Norma, Ali, Siraj M., Stephens, Phil J., Miller, Vincent A., Shyr, Yu, Guo, Yan, Reddy, Nishitha M., Kozhaya, Lina, Unutmaz, Derya, Chen, Xueyan, Irish, Jonathan M., Davé, Utpal P.
Publié dans JCO Precis Oncol (2018)

Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation

par Triplett, Todd A., Cardenas, Kim T., Lancaster, Jessica N., Hu, Zicheng, Selden, Hilary J., Jasso, Guadalupe J., Balasubramanyam, Sadhana, Chan, Kathy, Li, LiQi, Chen, Xi, Marcogliese, Andrea N., Davé, Utpal P., Love, Paul E., Ehrlich, Lauren I. R.
Publié dans Proc Natl Acad Sci U S A (2016)

PI3Kγ/δ and NOTCH1 cross-regulate pathways that define the T-cell acute lymphoblastic leukemia disease signature

par Efimenko, Evgeni, Davé, Utpal P., Lebedeva, Irina V., Shen, Yao, Sanchez-Quintero, Maria J., Diolaiti, Daniel, Kung, Andrew, Lannutti, Brian J., Chen, Jianchung, Realubit, Ronald, Niatsetskiya, Zoya, Ten, Vadim, Karan, Charles, Chen, Xi, Califano, Andrea, Diacovo, Thomas G.
Publié dans Mol Cancer Ther (2017)

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways

par Smith, Stephen, Tripathi, Rati, Goodings, Charnise, Cleveland, Susan, Mathias, Elizabeth, Hardaway, J. Andrew, Elliott, Natalina, Yi, Yajun, Chen, Xi, Downing, James, Mullighan, Charles, Swing, Deborah A., Tessarollo, Lino, Li, Liqi, Love, Paul, Jenkins, Nancy A., Copeland, Neal G., Thompson, Mary Ann, Du, Yang, Davé, Utpal P.
Publié 2014

Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

par Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea
Publié dans Nat Commun (2020)

Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

par Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea
Publié dans Nat Commun (2020)

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia

par Roels, Juliette, Thénoz, Morgan, Szarzyńska, Bronisława, Landfors, Mattias, De Coninck, Stien, Demoen, Lisa, Provez, Lien, Kuchmiy, Anna, Strubbe, Steven, Reunes, Lindy, Pieters, Tim, Matthijssens, Filip, Van Loocke, Wouter, Erarslan-Uysal, Büşra, Richter-Pechańska, Paulina, Declerck, Ken, Lammens, Tim, De Moerloose, Barbara, Deforce, Dieter, Van Nieuwerburgh, Filip, Cheung, Laurence C., Kotecha, Rishi S., Mansour, Marc R., Ghesquière, Bart, Van Camp, Guy, Berghe, Wim Vanden, Kowalczyk, Jerzy R., Szczepański, Tomasz, Davé, Utpal P., Kulozik, Andreas E., Goossens, Steven, Curtis, David J., Taghon, Tom, Dawidowska, Małgorzata, Degerman, Sofie, Van Vlierberghe, Pieter
Publié dans Blood Cancer Discov (2020)