Small Molecule Recognition of c-Src via the Imatinib-Binding Conformation

Por Dar, Arvin C., Lopez, Michael S., Shokat, Kevan M.
Publicado em 2008

Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling

Por Dhawan, Neil S., scopton, Alex P., Dar, Arvin C.
Publicado no Nature (2016)

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

Por Dar, Arvin C., Das, Tirtha K., Shokat, Kevan M., Cagan, Ross L.
Publicado em 2012

Slipped-strand DNAs formed by long (CAG)·(CTG) repeats: slipped-out repeats and slip-out junctions

Por Pearson, Christopher E., Tam, Mandy, Wang, Yuh-Hwa, Montgomery, S. Erin, Dar, Arvin C., Cleary, John D., Nichol, Kerrie
Publicado em 2002

Chemical Genetic Approach for Kinase-Substrate Mapping by Covalent Capture of Thiophosphopeptides and Analysis by Mass Spectrometry

Por Hertz, Nicholas T., Wang, Beatrice T., Allen, Jasmina J., Zhang, Chao, Dar, Arvin C., Burlingame, Alma L., Shokat, Kevan M.
Publicado em 2010

Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein

Por Seo, Eun Joo, Liu, Furong, Kawagishi-Kobayashi, Makiko, Ung, Tekly L., Cao, Chune, Dar, Arvin C., Sicheri, Frank, Dever, Thomas E.
Publicado em 2008

Structure-guided Inhibitor Design Expands the Scope of Analog-Sensitive Kinase Technology

Por Zhang, Chao, Lopez, Michael S., Dar, Arvin C., LaDow, Eva, Finkbeiner, Steven, Yun, Cai-Hong, Eck, Michael J., Shokat, Kevan M.
Publicado em 2013

Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors

Por Israelow, Benjamin, Mullokandov, Gavriel, Agudo, Judith, Sourisseau, Marion, Bashir, Ali, Maldonado, Andres Y., Dar, Arvin C., Brown, Brian D., Evans, Matthew J.
Publicado no Nat Commun (2014)

PKR and GCN2 Kinases and Guanine Nucleotide Exchange Factor Eukaryotic Translation Initiation Factor 2B (eIF2B) Recognize Overlapping Surfaces on eIF2α

Por Dey, Madhusudan, Trieselmann, Bruce, Locke, Emily G., Lu, Jingfang, Cao, Chune, Dar, Arvin C., Krishnamoorthy, Thanuja, Dong, Jinsheng, Sicheri, Frank, Dever, Thomas E.
Publicado em 2005

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

Por Mendez, Aaron S, Alfaro, Jennifer, Morales-Soto, Marisol A, Dar, Arvin C, McCullagh, Emma, Gotthardt, Katja, Li, Han, Acosta-Alvear, Diego, Sidrauski, Carmela, Korennykh, Alexei V, Bernales, Sebastian, Shokat, Kevan M, Walter, Peter
Publicado no eLife (2015)

CNS Anticancer Drug Discovery and Development Conference White Paper

Por Levin, Victor A., Tonge, Peter J., Gallo, James M., Birtwistle, Marc R., Dar, Arvin C., Iavarone, Antonio, Paddison, Patrick J., Heffron, Timothy P., Elmquist, William F., Lachowicz, Jean E., Johnson, Ted W., White, Forest M., Sul, Joohee, Smith, Quentin R., Shen, Wang, Sarkaria, Jann N., Samala, Ramakrishna, Wen, Patrick Y., Berry, Donald A., Petter, Russell C.
Publicado no Neuro Oncol (2015)