Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors

Hepatitis C virus (HCV) replication is dependent on a liver-specific microRNA (miRNA), miR-122. A recent clinical trial reported that transient inhibition of miR-122 reduced viral titers in HCV infected patients. Here we set out to better understand how miR-122 inhibition influences HCV replication...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Israelow, Benjamin, Mullokandov, Gavriel, Agudo, Judith, Sourisseau, Marion, Bashir, Ali, Maldonado, Andres Y., Dar, Arvin C., Brown, Brian D., Evans, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236719/
https://ncbi.nlm.nih.gov/pubmed/25403145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6408
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados