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Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors
Hepatitis C virus (HCV) replication is dependent on a liver-specific microRNA (miRNA), miR-122. A recent clinical trial reported that transient inhibition of miR-122 reduced viral titers in HCV infected patients. Here we set out to better understand how miR-122 inhibition influences HCV replication...
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| Foilsithe in: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236719/ https://ncbi.nlm.nih.gov/pubmed/25403145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6408 |
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