Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans

द्वारा Graham, Mark J., Viney, Nick, Crooke, Rosanne M., Tsimikas, Sotirios
में प्रकाशित J Lipid Res (2016)

In Vivo Antisense Oligonucleotide Reduction of NPC1 Expression as a Novel Mouse Model for Niemann Pick Type C– Associated Liver Disease

द्वारा Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
प्रकाशित 2008

TNF-α plays a role in hepatocyte apoptosis in Niemann-Pick type C liver disease

द्वारा Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
प्रकाशित 2009

Antisense technology: A review

द्वारा Crooke, Stanley T., Liang, Xue-Hai, Baker, Brenda F., Crooke, Rosanne M.
में प्रकाशित J Biol Chem (2021)

Recovery from liver disease in a Niemann-Pick type C mouse model

द्वारा Sayre, Naomi L., Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
प्रकाशित 2010

Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism

द्वारा Li, Guoping, Hernandez-Ono, Antonio, Crooke, Rosanne M., Graham, Mark J., Ginsberg, Henry N.
प्रकाशित 2011

Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure, and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type di...

द्वारा Li, Guoping, Hernandez-Ono, Antonio, Crooke, Rosanne M., Graham, Mark J., Ginsberg, Henry N.
प्रकाशित 2011

Antisense Technology: An Emerging Platform for Cardiovascular Disease Therapeutics

द्वारा Lee, Richard G., Crosby, Jeff, Baker, Brenda F., Graham, Mark J., Crooke, Rosanne M.
प्रकाशित 2013

Evaluation of an Anti-Tumor Necrosis Factor Therapeutic in a Mouse Model of Niemann-Pick C Liver Disease

द्वारा Vincent, Melanie, Sayre, Naomi L., Graham, Mark J., Crooke, Rosanne M., Shealy, David J., Liscum, Laura
प्रकाशित 2010

CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation

द्वारा Donner, Aaron J, Yeh, Steve T, Hung, Gene, Graham, Mark J, Crooke, Rosanne M, Mullick, Adam E
में प्रकाशित Mol Ther Nucleic Acids (2015)

Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice

द्वारा Carr, Rotonya M., Patel, Rajesh T., Rao, Vandana, Dhir, Ravindra, Graham, Mark J., Crooke, Rosanne M., Ahima, Rexford S.
प्रकाशित 2012

Lowering apolipoprotein CIII delays onset of type 1 diabetes

द्वारा Holmberg, Rebecka, Refai, Essam, Höög, Anders, Crooke, Rosanne M., Graham, Mark, Olivecrona, Gunilla, Berggren, Per-Olof, Juntti-Berggren, Lisa
प्रकाशित 2011

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr(−/−) mice

द्वारा Bell, Thomas A., Graham, Mark J., Lee, Richard G., Mullick, Adam E., Fu, Wuxia, Norris, Dan, Crooke, Rosanne M.
प्रकाशित 2013

Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

द्वारा Wu, Chia-Hua, Wang, Ya, Ma, Murong, Mullick, Adam E., Crooke, Rosanne M., Graham, Mark J., Daugherty, Alan, Lu, Hong S.
में प्रकाशित Biosci Rep (2019)

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice

द्वारा Mullick, Adam E., Fu, Wuxia, Graham, Mark J., Lee, Richard G., Witchell, Donna, Bell, Thomas A., Whipple, Charles P., Crooke, Rosanne M.
प्रकाशित 2011

Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice

द्वारा Xie, Yan, Fung, Ho Yee Joyce, Newberry, Elizabeth P., Kennedy, Susan, Luo, Jianyang, Crooke, Rosanne M., Graham, Mark J., Davidson, Nicholas O.
प्रकाशित 2014

Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp (−/−) mice

द्वारा Newberry, Elizabeth P., Kennedy, Susan M., Xie, Yan, Luo, Jianyang, Crooke, Rosanne M., Graham, Mark J., Fu, Jin, Piomelli, Daniele, Davidson, Nicholas O.
प्रकाशित 2012

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

द्वारा Lee, Richard G., Fu, Wuxia, Graham, Mark J., Mullick, Adam E., Sipe, Donna, Gattis, Danielle, Bell, Thomas A., Booten, Sheri, Crooke, Rosanne M.
प्रकाशित 2013

Effects of an Antisense Oligonucleotide Inhibitor of C‐Reactive Protein Synthesis on the Endotoxin Challenge Response in Healthy Human Male Volunteers

द्वारा Noveck, Robert, Stroes, Erik S. G., Flaim, JoAnn D., Baker, Brenda F., Hughes, Steve, Graham, Mark J., Crooke, Rosanne M., Ridker, Paul M
में प्रकाशित J Am Heart Assoc (2014)

Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in Liver fatty acid binding protein null mice

द्वारा Newberry, Elizabeth P., Xie, Yan, Kennedy, Susan M., Graham, Mark J., Crooke, Rosanne M., Jiang, Hui, Chen, Anping, Ory, Daniel S., Davidson, Nicholas O.
में प्रकाशित Hepatology (2017)