Lowering apolipoprotein CIII delays onset of type 1 diabetes

Serum levels of apolipoprotein CIII (apoCIII) are increased in type 1 diabetic patients, and when β cells are exposed to these diabetic sera, apoptosis occurs, an effect abolished by an antibody against apoCIII. We have investigated the BB rat, an animal model that develops a human-like type 1 diabe...

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Main Authors: Holmberg, Rebecka, Refai, Essam, Höög, Anders, Crooke, Rosanne M., Graham, Mark, Olivecrona, Gunilla, Berggren, Per-Olof, Juntti-Berggren, Lisa
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127896/
https://ncbi.nlm.nih.gov/pubmed/21670290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019553108
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