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Apolipoprotein CIII promotes Ca(2+)-dependent β cell death in type 1 diabetes
In type 1 diabetes (T1D), there is a specific destruction of the insulin secreting pancreatic β cell. Although the exact molecular mechanisms underlying β cell destruction are not known, sera from T1D patients have been shown to promote Ca(2+)-induced apoptosis. We now demonstrate that apolipoprotei...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC454169/ https://ncbi.nlm.nih.gov/pubmed/15210953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403551101 |
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