Transthyretin constitutes a functional component in pancreatic β-cell stimulus-secretion coupling

Transthyretin (TTR) is a transport protein for thyroxine and, in association with retinol-binding protein, for retinol, mainly existing as a tetramer in vivo. We now demonstrate that TTR tetramer has a positive role in pancreatic β-cell stimulus-secretion coupling. TTR promoted glucose-induced incre...

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Detalhes bibliográficos
Main Authors: Refai, Essam, Dekki, Nancy, Yang, Shao-Nian, Imreh, Gabriela, Cabrera, Over, Yu, Lina, Yang, Guang, Norgren, Svante, Rössner, Sophia M., Inverardi, Luca, Ricordi, Camillo, Olivecrona, Gunilla, Andersson, Mats, Jörnvall, Hans, Berggren, Per-Olof, Juntti-Berggren, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287967/
https://ncbi.nlm.nih.gov/pubmed/16286652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503219102
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