Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

Angiotensinogen (AGT) is the unique substrate of all angiotensin peptides. We review the recent preclinical research of AGT antisense oligonucleotides (ASOs), a rapidly evolving therapeutic approach. The scope of the research findings not only opens doors for potentially new therapeutics of hyperten...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Wu, Chia-Hua, Wang, Ya, Ma, Murong, Mullick, Adam E., Crooke, Rosanne M., Graham, Mark J., Daugherty, Alan, Lu, Hong S.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2019
Matèries:
Review Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328882/
https://ncbi.nlm.nih.gov/pubmed/30530571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180201
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