Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis

OBJECTIVE: Angiotensinogen (AGT) is the unique precursor of the renin-angiotensin system that is sequentially cleaved by renin and angiotensin-converting enzyme (ACE) to produce angiotensin II (AngII). In this study, we determined how these renin-angiotensin components interact with megalin in kidne...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Ye, Feiming, Wang, Ya, Wu, Congqing, Howatt, Deborah A., Wu, Chia-Hua, Balakrishnan, Anju, Mullick, Adam E., Graham, Mark J., Danser, A.H. Jan, Wang, Jian’an, Daugherty, Alan, Lu, Hong S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344256/
https://ncbi.nlm.nih.gov/pubmed/30567480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311817
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