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Angiotensin-Converting Enzyme in Smooth Muscle Cells Promotes Atherosclerosis

OBJECTIVE: Angiotensin-converting enzyme (ACE) is present in many cell types of atherosclerotic lesions. This study determined whether ACE activity in endothelium and smooth muscle cells (SMCs), two major resident cell types of the aorta, contributes to hypercholesterolemia-induced atherosclerosis....

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Chen, Xiaofeng, Howatt, Deborah A., Balakrishnan, Anju, Moorleghen, Jessica J., Wu, Congqing, Cassis, Lisa A., Daugherty, Alan, Lu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882263/
https://ncbi.nlm.nih.gov/pubmed/27055902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307038
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