Fibroblast Angiotensin II Type 1a Receptors Contribute to Angiotensin II-Induced Medial Hyperplasia in the Ascending Aorta

OBJECTIVE: Angiotensin II (AngII) infusion causes aortic medial thickening via stimulation of AT1a receptors. The purpose of this study was to determine the cellular loci of AT1a receptors that mediate this AngII-induced aortic pathology. APPROACH AND RESULTS: Saline or AngII was infused into AT1a r...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Poduri, Aruna, Rateri, Debra L., Howatt, Deborah A., Balakrishnan, Anju, Moorleghen, Jessica J., Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552596/
https://ncbi.nlm.nih.gov/pubmed/26160957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305995
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