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Endothelial Cell-specific Deficiency of AngII Type 1a Receptors Attenuates AngII-induced Ascending Aortic Aneurysms in LDL Receptor −/− Mice
RATIONALE: Human studies and mouse models have provided evidence for angiotensin II (AngII)-based mechanisms as an underlying cause of aneurysms localized to the ascending aorta. In agreement with this associative evidence, we have published recently that AngII infusion induces aneurysmal pathology...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076204/ https://ncbi.nlm.nih.gov/pubmed/21252156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.222844 |
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