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TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions

AngII and TGF-β interact in development of thoracic and abdominal aortic diseases, although there are many facets of this interaction that have not been clearly defined. The aim of the present study was to determine the effects of TGF-β neutralization on AngII induced-aortic pathologies. Male C57BL/...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Xiaofeng, Rateri, Debra L., Howatt, Deborah A., Balakrishnan, Anju, Moorleghen, Jessica J., Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841552/
https://ncbi.nlm.nih.gov/pubmed/27104863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153811
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