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TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions

AngII and TGF-β interact in development of thoracic and abdominal aortic diseases, although there are many facets of this interaction that have not been clearly defined. The aim of the present study was to determine the effects of TGF-β neutralization on AngII induced-aortic pathologies. Male C57BL/...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Chen, Xiaofeng, Rateri, Debra L., Howatt, Deborah A., Balakrishnan, Anju, Moorleghen, Jessica J., Cassis, Lisa A., Daugherty, Alan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841552/
https://ncbi.nlm.nih.gov/pubmed/27104863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153811
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