Smooth Muscle Cell Deletion of LDL Receptor Related Protein-1 Augments AngII-Induced Superior Mesenteric Arterial and Ascending Aortic Aneurysms

OBJECTIVE: LRP1, a multifunctional protein involved in endocytosis and cell signaling pathways, leads to a range of vascular pathologies when deleted in vascular smooth muscle cells (SMCs). The purpose of this study was to determine whether LRP1 deletion in SMCs influenced AngII-induced arterial pat...

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Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Davis, Frank M., Rateri, Debra L., Balakrishnan, Anju, Howatt, Deborah A., Strickland, Dudley K., Muratoglu, Selen C., Haggerty, Christopher M., Fornwalt, Brandon K., Cassis, Lisa A., Daugherty, Alan
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332619/
https://ncbi.nlm.nih.gov/pubmed/25395615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304683
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