Endothelial Cell-specific Deficiency of AngII Type 1a Receptors Attenuates AngII-induced Ascending Aortic Aneurysms in LDL Receptor −/− Mice

RATIONALE: Human studies and mouse models have provided evidence for angiotensin II (AngII)-based mechanisms as an underlying cause of aneurysms localized to the ascending aorta. In agreement with this associative evidence, we have published recently that AngII infusion induces aneurysmal pathology...

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Main Authors: Rateri, Debra L., Moorleghen, Jessica J., Balakrishnan, Anju, Owens, A. Phillip, Howatt, Deborah A., Subramanian, Venkateswaran, Poduri, Aruna, Charnigo, Richard, Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076204/
https://ncbi.nlm.nih.gov/pubmed/21252156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.222844
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