Depletion of Endothelial or Smooth Muscle Cell-Specific Angiotensin II Type 1a Receptors Does Not Influence Aortic Aneurysms or Atherosclerosis in LDL Receptor Deficient Mice

BACKGROUND: Whole body genetic deletion of AT1a receptors in mice uniformly reduces hypercholesterolemia and angiotensin II-(AngII) induced atherosclerosis and abdominal aortic aneurysms (AAAs). However, the role of AT1a receptor stimulation of principal cell types resident in the arterial wall rema...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rateri, Debra L., Moorleghen, Jessica J., Knight, Victoria, Balakrishnan, Anju, Howatt, Deborah A., Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517567/
https://ncbi.nlm.nih.gov/pubmed/23236507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051483
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares