Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans

nork Graham, Mark J., Viney, Nick, Crooke, Rosanne M., Tsimikas, Sotirios
Argitaratua izan da J Lipid Res (2016)

In Vivo Antisense Oligonucleotide Reduction of NPC1 Expression as a Novel Mouse Model for Niemann Pick Type C– Associated Liver Disease

nork Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
Argitaratua 2008

TNF-α plays a role in hepatocyte apoptosis in Niemann-Pick type C liver disease

nork Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
Argitaratua 2009

Antisense technology: A review

nork Crooke, Stanley T., Liang, Xue-Hai, Baker, Brenda F., Crooke, Rosanne M.
Argitaratua izan da J Biol Chem (2021)

Recovery from liver disease in a Niemann-Pick type C mouse model

nork Sayre, Naomi L., Rimkunas, Victoria M., Graham, Mark J., Crooke, Rosanne M., Liscum, Laura
Argitaratua 2010

Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism

nork Li, Guoping, Hernandez-Ono, Antonio, Crooke, Rosanne M., Graham, Mark J., Ginsberg, Henry N.
Argitaratua 2011

Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure, and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type di...

nork Li, Guoping, Hernandez-Ono, Antonio, Crooke, Rosanne M., Graham, Mark J., Ginsberg, Henry N.
Argitaratua 2011

Antisense Technology: An Emerging Platform for Cardiovascular Disease Therapeutics

nork Lee, Richard G., Crosby, Jeff, Baker, Brenda F., Graham, Mark J., Crooke, Rosanne M.
Argitaratua 2013

Evaluation of an Anti-Tumor Necrosis Factor Therapeutic in a Mouse Model of Niemann-Pick C Liver Disease

nork Vincent, Melanie, Sayre, Naomi L., Graham, Mark J., Crooke, Rosanne M., Shealy, David J., Liscum, Laura
Argitaratua 2010

CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation

nork Donner, Aaron J, Yeh, Steve T, Hung, Gene, Graham, Mark J, Crooke, Rosanne M, Mullick, Adam E
Argitaratua izan da Mol Ther Nucleic Acids (2015)

Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice

nork Carr, Rotonya M., Patel, Rajesh T., Rao, Vandana, Dhir, Ravindra, Graham, Mark J., Crooke, Rosanne M., Ahima, Rexford S.
Argitaratua 2012

Lowering apolipoprotein CIII delays onset of type 1 diabetes

nork Holmberg, Rebecka, Refai, Essam, Höög, Anders, Crooke, Rosanne M., Graham, Mark, Olivecrona, Gunilla, Berggren, Per-Olof, Juntti-Berggren, Lisa
Argitaratua 2011

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr(−/−) mice

nork Bell, Thomas A., Graham, Mark J., Lee, Richard G., Mullick, Adam E., Fu, Wuxia, Norris, Dan, Crooke, Rosanne M.
Argitaratua 2013

Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

nork Wu, Chia-Hua, Wang, Ya, Ma, Murong, Mullick, Adam E., Crooke, Rosanne M., Graham, Mark J., Daugherty, Alan, Lu, Hong S.
Argitaratua izan da Biosci Rep (2019)

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice

nork Mullick, Adam E., Fu, Wuxia, Graham, Mark J., Lee, Richard G., Witchell, Donna, Bell, Thomas A., Whipple, Charles P., Crooke, Rosanne M.
Argitaratua 2011

Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice

nork Xie, Yan, Fung, Ho Yee Joyce, Newberry, Elizabeth P., Kennedy, Susan, Luo, Jianyang, Crooke, Rosanne M., Graham, Mark J., Davidson, Nicholas O.
Argitaratua 2014

Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp (−/−) mice

nork Newberry, Elizabeth P., Kennedy, Susan M., Xie, Yan, Luo, Jianyang, Crooke, Rosanne M., Graham, Mark J., Fu, Jin, Piomelli, Daniele, Davidson, Nicholas O.
Argitaratua 2012

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

nork Lee, Richard G., Fu, Wuxia, Graham, Mark J., Mullick, Adam E., Sipe, Donna, Gattis, Danielle, Bell, Thomas A., Booten, Sheri, Crooke, Rosanne M.
Argitaratua 2013

Effects of an Antisense Oligonucleotide Inhibitor of C‐Reactive Protein Synthesis on the Endotoxin Challenge Response in Healthy Human Male Volunteers

nork Noveck, Robert, Stroes, Erik S. G., Flaim, JoAnn D., Baker, Brenda F., Hughes, Steve, Graham, Mark J., Crooke, Rosanne M., Ridker, Paul M
Argitaratua izan da J Am Heart Assoc (2014)

Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in Liver fatty acid binding protein null mice

nork Newberry, Elizabeth P., Xie, Yan, Kennedy, Susan M., Graham, Mark J., Crooke, Rosanne M., Jiang, Hui, Chen, Anping, Ory, Daniel S., Davidson, Nicholas O.
Argitaratua izan da Hepatology (2017)