Repression of β-catenin function in malignant cells by nonsteroidal antiinflammatory drugs

av Lu, Desheng, Cottam, Howard B., Corr, Maripat, Carson, Dennis A.
Publicerad 2005

A Novel Assay Principle for Modulators of Protein-Protein Interactions and its Application to non-ATP-Competitive Ligands Targeting Protein Kinase A

av Saldanha, S. Adrian, Kaler, Gregory, Cottam, Howard B., Abagyan, Ruben, Taylor, Susan S.
Publicerad 2006

Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

av Shukla, Nikunj M., Chan, Michael, Hayashi, Tomoko, Carson, Dennis A., Cottam, Howard B.
I publikationen ACS Med Chem Lett (2018)

Hypoestoxide inhibits tumor growth in the mouse CT26 colon tumor model

av Ojo-Amaize, Emmanuel A, Cottam, Howard B, Oyemade, Olusola A, Okogun, Joseph I, Nchekwube, Emeka J
I publikationen World J Gastroenterol (2007)

Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model

av Enzler, Thomas, Sano, Yasuyo, Choo, Min-Kyung, Cottam, Howard B., Karin, Michael, Tsao, Hensin, Park, Jin Mo
Publicerad 2011

Mast Cell-Mediated Inhibition of Abdominal Neutrophil Inflammation by a PEGylated TLR7 Ligand

av Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Cottam, Howard B., Lao, Fitzgerald, Carson, Dennis A., Corr, Maripat
Publicerad 2012

Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs

av Brown, Simon H.J., Cheng, Cecilia Y., Saldanha, S. Adrian, Wu, Jian, Cottam, Howard B, Sankaran, Banumathi, Taylor, Susan S.
Publicerad 2013

Novel Synthetic Toll-Like Receptor 4/MD2 Ligands Attenuate Sterile Inflammation

av Hayashi, Tomoko, Crain, Brian, Yao, Shiyin, Caneda, Christa D., Cottam, Howard B., Chan, Michael, Corr, Maripat, Carson, Dennis A.
Publicerad 2014

Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/β-catenin signaling and CLL cell survival

av Jin, Guangyi, Lu, Desheng, Yao, Shiyin, Wu, Christina C. N., Liu, Jerry X., Carson, Dennis A., Cottam, Howard B.
I publikationen Bioorg Med Chem Lett (2008)

Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

av Lee, Jongdae, Chuang, Tsung-Hsien, Redecke, Vanessa, She, Liping, Pitha, Paula M., Carson, Dennis A., Raz, Eyal, Cottam, Howard B.
Publicerad 2003

Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer

av Hayashi, Tomoko, Crain, Brian, Corr, Maripat, Chan, Michael, Cottam, Howard B, Maj, Roberto, Barberis, Alcide, Leoni, Lorenzo, Carson, Dennis A
Publicerad 2010

Induction of an apoptotic program in cell-free extracts by 2-chloro-2′-deoxyadenosine 5′-triphosphate and cytochrome c

av Leoni, Lorenzo M., Chao, Qi, Cottam, Howard B., Genini, Davide, Rosenbach, Michael, Carrera, Carlos J., Budihardjo, Imawati, Wang, Xiaodong, Carson, Dennis A.
Publicerad 1998

Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

av Lu, Desheng, Zhao, Yandong, Tawatao, Rommel, Cottam, Howard B., Sen, Malini, Leoni, Lorenzo M., Kipps, Thomas J., Corr, Maripat, Carson, Dennis A.
Publicerad 2004

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

av Wu, Christina C. N., Hayashi, Tomoko, Takabayashi, Kenji, Sabet, Mojgan, Smee, Donald F., Guiney, Donald D., Cottam, Howard B., Carson, Dennis A.
Publicerad 2007

Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

av Chan, Michael, Hayashi, Tomoko, Kuy, Crystal S., Gray, Christine S., Wu, Christina C. N., Corr, Maripat, Wrasidlo, Wolfgang, Cottam, Howard B., Carson, Dennis A.
Publicerad 2009

Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7

av Hayashi, Tomoko, Cottam, Howard B., Chan, Michael, Jin, Guangyi, Tawatao, Rommel I., Crain, Brian, Ronacher, Lisa, Messer, Karen, Carson, Dennis A., Corr, Maripat
Publicerad 2008

Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

av Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Promessi, Victor J., Shyu, Luke, Sheng, Caroline, Kang, McNancy, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
I publikationen PLoS One (2015)

Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

av Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Tawatao, Rommel I., Gray, Christine, Vuong, Linda, Lao, Fitzgerald, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Publicerad 2012

Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

av Hosoya, Tadashi, Shukla, Nikunj M., Fujita, Yuya, Yao, Shiyin, Lao, Fitzgerald S., Baba, Hiroyuki, Yasuda, Shinsuke, Cottam, Howard B., Carson, Dennis A., Hayashi, Tomoko, Corr, Maripat
I publikationen Front Pharmacol (2020)

The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis

av Kolluri, Siva Kumar, Corr, Maripat, James, Sharon Y., Bernasconi, Michele, Lu, Desheng, Liu, Wen, Cottam, Howard B., Leoni, Lorenzo M., Carson, Dennis A., Zhang, Xiao-kun
Publicerad 2005