Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

The Toll-like receptors (TLR) have been advocated as attractive therapeutic targets because TLR signaling plays dual roles in initiating adaptive immune responses and perpetuating inflammation. Paradoxically, repeated stimulation of bone marrow mononuclear cells with a synthetic TLR7 ligand 9-benzyl...

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Main Authors: Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Tawatao, Rommel I., Gray, Christine, Vuong, Linda, Lao, Fitzgerald, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461028/
https://ncbi.nlm.nih.gov/pubmed/23029281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045860
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