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Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System
The Toll-like receptors (TLR) have been advocated as attractive therapeutic targets because TLR signaling plays dual roles in initiating adaptive immune responses and perpetuating inflammation. Paradoxically, repeated stimulation of bone marrow mononuclear cells with a synthetic TLR7 ligand 9-benzyl...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461028/ https://ncbi.nlm.nih.gov/pubmed/23029281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045860 |
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