Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

The Toll-like receptors (TLR) have been advocated as attractive therapeutic targets because TLR signaling plays dual roles in initiating adaptive immune responses and perpetuating inflammation. Paradoxically, repeated stimulation of bone marrow mononuclear cells with a synthetic TLR7 ligand 9-benzyl...

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Библиографические подробности
Главные авторы: Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Tawatao, Rommel I., Gray, Christine, Vuong, Linda, Lao, Fitzgerald, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461028/
https://ncbi.nlm.nih.gov/pubmed/23029281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045860
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