Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

The Toll-like receptors (TLR) have been advocated as attractive therapeutic targets because TLR signaling plays dual roles in initiating adaptive immune responses and perpetuating inflammation. Paradoxically, repeated stimulation of bone marrow mononuclear cells with a synthetic TLR7 ligand 9-benzyl...

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Bibliografiske detaljer
Main Authors: Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Tawatao, Rommel I., Gray, Christine, Vuong, Linda, Lao, Fitzgerald, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461028/
https://ncbi.nlm.nih.gov/pubmed/23029281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045860
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