Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

Autoimmune diabetes mellitus (DM) results from the destruction of pancreatic islet cells by activated T lymphocytes, which have been primed by activated dendritic cells (DC). Individualized therapy with ex vivo DC manipulation and reinfusion has been proposed as a treatment for DM, but this treatmen...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Promessi, Victor J., Shyu, Luke, Sheng, Caroline, Kang, McNancy, Cottam, Howard B., Carson, Dennis A., Corr, Maripat
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468074/
https://ncbi.nlm.nih.gov/pubmed/26076454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129867
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky