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Repression of β-catenin function in malignant cells by nonsteroidal antiinflammatory drugs

Activation of the Wnt/β-catenin pathway promotes the development of several cancers and is an attractive target for chemopreventive and chemotherapeutic agents. Nonsteroidal antiinflammatory drugs (NSAIDs) have been reported to antagonize β-catenin function, but their mechanism of action is not know...

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Bibliografiske detaljer
Main Authors: Lu, Desheng, Cottam, Howard B., Corr, Maripat, Carson, Dennis A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317972/
https://ncbi.nlm.nih.gov/pubmed/16352713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509316102
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