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Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators

[Image: see text] Activation of Toll-like receptors (TLRs) located on immune cells leads to induction of immune responses that can be useful in vaccines for infectious diseases, cancer immunotherapy, and autoimmune diseases. Novel TLR signaling pathway modulators can further enhance the efficacy of...

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Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Shukla, Nikunj M., Chan, Michael, Hayashi, Tomoko, Carson, Dennis A., Cottam, Howard B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295859/
https://ncbi.nlm.nih.gov/pubmed/30613317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00566
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