Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

B cell chronic lymphocytic leukemia (CLL) is characterized by an accumulation of mature, functionally incompetent B cells. Wnts are a large family of secreted glycoproteins involved in cell proliferation, differentiation, and oncogenesis. The classical Wnt signaling cascade inhibits the activity of...

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Autors principals: Lu, Desheng, Zhao, Yandong, Tawatao, Rommel, Cottam, Howard B., Sen, Malini, Leoni, Lorenzo M., Kipps, Thomas J., Corr, Maripat, Carson, Dennis A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC365753/
https://ncbi.nlm.nih.gov/pubmed/14973184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308648100
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