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Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway

BACKGROUND: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/β-catenin signaling promotes the development of several cancers and is an attractive target for chemopreventive and chemotherapeutic agents. RESULTS: In...

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Detalles Bibliográficos
Main Authors: Lu, Desheng, Carson, Dennis A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789054/
https://ncbi.nlm.nih.gov/pubmed/19948059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-13
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