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Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

Salinomycin, an antibiotic potassium ionophore, has been reported recently to act as a selective breast cancer stem cell inhibitor, but the biochemical basis for its anticancer effects is not clear. The Wnt/β-catenin signal transduction pathway plays a central role in stem cell development, and its...

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Main Authors: Lu, Desheng, Choi, Michael Y., Yu, Jian, Castro, Januario E., Kipps, Thomas J., Carson, Dennis A.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156152/
https://ncbi.nlm.nih.gov/pubmed/21788521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110431108
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