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Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia
Recent studies show that redox-active small molecules are selectively cytotoxic to chronic lymphocytic leukemia (CLL). Although elevated levels of reactive oxygen species in CLL cells have been implicated, the molecular mechanism underlying this selectivity is unclear. In other cell types, the nucle...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867719/ https://ncbi.nlm.nih.gov/pubmed/20368435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002890107 |
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