Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II

Por Core, Leighton J., Lis, John T.
Publicado em 2008

Paused Pol II captures enhancer activity and acts as a potent insulator

Por Core, Leighton J., Lis, John T.
Publicado em 2009

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

Por Core, Leighton J., Waterfall, Joshua J., Lis, John T.
Publicado em 2008

Precise Maps of RNA Polymerase Reveal How Promoters Direct Initiation and Pausing

Por Kwak, Hojoong, Fuda, Nicholas J., Core, Leighton J., Lis, John T.
Publicado em 2013

Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription

Por Saunders, Abbie, Core, Leighton J., Sutcliffe, Catherine, Lis, John T., Ashe, Hilary L.
Publicado em 2013

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

Por Kruesi, William S, Core, Leighton J, Waters, Colin T, Lis, John T, Meyer, Barbara J
Publicado em 2013

Postrecruitment Regulation of RNA Polymerase II Directs Rapid Signaling Responses at the Promoters of Estrogen Target Genes

Por Kininis, Miltiadis, Isaacs, Gary D., Core, Leighton J., Hah, Nasun, Kraus, W. Lee
Publicado em 2009

The Polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo

Por Chopra, Vivek S., Hendrix, David A., Core, Leighton J., Tsui, Chiahao, Lis, John T., Levine, Michael
Publicado em 2011

Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

Por Core, Leighton J., Martins, André L., Danko, Charles G., Waters, Colin, Siepel, Adam, Lis, John T.
Publicado no Nat Genet (2014)

Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells

Por Min, Irene M., Waterfall, Joshua J., Core, Leighton J., Munroe, Robert J., Schimenti, John, Lis, John T.
Publicado em 2011

Fcp1 Dephosphorylation of the RNA Polymerase II C-Terminal Domain Is Required for Efficient Transcription of Heat Shock Genes

Por Fuda, Nicholas J., Buckley, Martin S., Wei, Wenxiang, Core, Leighton J., Waters, Colin T., Reinberg, Danny, Lis, John T.
Publicado em 2012

Bacillus subtilis RapA Phosphatase Domain Interaction with Its Substrate, Phosphorylated Spo0F, and Its Inhibitor, the PhrA Peptide

Por Diaz, Alejandra R., Core, Leighton J., Jiang, Min, Morelli, Michela, Chiang, Christina H., Szurmant, Hendrik, Perego, Marta
Publicado em 2012

Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation

Por Duarte, Fabiana M., Fuda, Nicholas J., Mahat, Dig B., Core, Leighton J., Guertin, Michael J., Lis, John T.
Publicado no Genes Dev (2016)

Defining the Status of RNA Polymerase at Promoters

Por Core, Leighton J., Waterfall, Joshua J., Gilchrist, Daniel A., Fargo, David C., Kwak, Hojoong, Adelman, Karen, Lis, John T.
Publicado em 2012

Pol II docking and pausing at growth and stress genes in C. elegans

Por Maxwell, Colin S., Kruesi, William S., Core, Leighton J., Kurhanewicz, Nicole, Waters, Colin T., Lewarch, Caitlin L., Antoshechkin, Igor, Lis, John T., Meyer, Barbara J., Baugh, L. Ryan
Publicado em 2014

Base-Pair Resolution Genome-Wide Mapping Of Active RNA polymerases using Precision Nuclear Run-On (PRO-seq)

Por Mahat, Dig Bijay, Kwak, Hojoong, Booth, Gregory T., Jonkers, Iris H., Danko, Charles G., Patel, Ravi K., Waters, Colin T., Munson, Katie, Core, Leighton J., Lis, John T.
Publicado no Nat Protoc (2016)

Identification of active transcriptional regulatory elements with GRO-seq

Por Danko, Charles G., Hyland, Stephanie L., Core, Leighton J., Martins, Andre L., Waters, Colin T, Lee, Hyung Won, Cheung, Vivian G., Kraus, W. Lee, Lis, John T., Siepel, Adam
Publicado no Nat Methods (2015)

RNA-DNA Differences Are Generated in Human Cells within Seconds After RNA Exits Pol II

Por Wang, Isabel X., Core, Leighton J., Kwak, Hojoong, Brady, Lauren, Bruzel, Alan, McDaniel, Lee, Richards, Allison L., Wu, Ming, Grunseich, Christopher, Lis, John T., Cheung, Vivian G.
Publicado no Cell Rep (2014)

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription

Por Kilpinen, Helena, Waszak, Sebastian M, Gschwind, Andreas R, Raghav, Sunil K, Witwicki, Robert M, Orioli, Andrea, Migliavacca, Eugenia, Wiederkehr, Michaël, Gutierrez-Arcelus, Maria, Panousis, Nikolaos, Yurovsky, Alisa, Lappalainen, Tuuli, Romano-Palumbo, Luciana, Planchon, Alexandra, Bielser, Deborah, Bryois, Julien, Padioleau, Ismael, Udin, Gilles, Thurnheer, Sarah, Hacker, David, Core, Leighton J, Lis, John T, Hernandez, Nouria, Reymond, Alexandre, Deplancke, Bart, Dermitzakis, Emmanouil T
Publicado no Science (2013)