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Fcp1 Dephosphorylation of the RNA Polymerase II C-Terminal Domain Is Required for Efficient Transcription of Heat Shock Genes

Fcp1 dephosphorylates the C-terminal domain of the largest subunit of RNA polymerase II (Pol II) to recycle it into a form that can initiate a new round of transcription. Previously, we identified Drosophila Fcp1 as an important factor in optimal Hsp70 mRNA accumulation after heat shock. Here, we ex...

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Detalhes bibliográficos
Main Authors: Fuda, Nicholas J., Buckley, Martin S., Wei, Wenxiang, Core, Leighton J., Waters, Colin T., Reinberg, Danny, Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421999/
https://ncbi.nlm.nih.gov/pubmed/22733996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00247-12
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