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Identification of active transcriptional regulatory elements with GRO-seq
Transcriptional regulatory elements (TREs), including enhancers and promoters, determine the transcription levels of associated genes. We have recently shown that global run-on and sequencing (GRO-seq) with enrichment for 5'-capped RNAs reveals active TREs with high accuracy. Here, we demonstra...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507281/ https://ncbi.nlm.nih.gov/pubmed/25799441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3329 |
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