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Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

Despite the conventional distinction between them, promoters and enhancers share many features in mammals, including divergent transcription and similar modes of transcription factor binding. Here, we examine the architecture of transcription initiation through comprehensive mapping of transcription...

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Bibliographic Details
Published in:Nat Genet
Main Authors: Core, Leighton J., Martins, André L., Danko, Charles G., Waters, Colin, Siepel, Adam, Lis, John T.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254663/
https://ncbi.nlm.nih.gov/pubmed/25383968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3142
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