Identification of active transcriptional regulatory elements with GRO-seq

Transcriptional regulatory elements (TREs), including enhancers and promoters, determine the transcription levels of associated genes. We have recently shown that global run-on and sequencing (GRO-seq) with enrichment for 5'-capped RNAs reveals active TREs with high accuracy. Here, we demonstra...

Full description

Saved in:
Bibliographic Details
Published in:Nat Methods
Main Authors: Danko, Charles G., Hyland, Stephanie L., Core, Leighton J., Martins, Andre L., Waters, Colin T, Lee, Hyung Won, Cheung, Vivian G., Kraus, W. Lee, Lis, John T., Siepel, Adam
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507281/
https://ncbi.nlm.nih.gov/pubmed/25799441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3329
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items