Dynamic evolution of regulatory element ensembles in primate CD4+ T-cells

How evolutionary changes at enhancers affect the transcription of target genes remains an important open question. Previous comparative studies of gene expression have largely measured the abundance of mRNA, which is affected by post-transcriptional regulatory processes, hence limiting inferences ab...

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Bibliografske podrobnosti
izdano v:Nat Ecol Evol
Main Authors: Danko, Charles G., Choate, Lauren A., Marks, Brooke A., Rice, Edward J., Wang, Zhong, Chu, Tinyi, Martins, Andre L., Dukler, Noah, Coonrod, Scott A., Tait Wojno, Elia D., Lis, John T., Kraus, W. Lee, Siepel, Adam
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957490/
https://ncbi.nlm.nih.gov/pubmed/29379187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-017-0447-5
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