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A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer
Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for endocrine resistance in breast cancer. We show that G...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5882141/ https://ncbi.nlm.nih.gov/pubmed/29614078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194522 |
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