A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer

Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for endocrine resistance in breast cancer. We show that G...

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Publicat a:PLoS One
Autors principals: Horibata, Sachi, Rice, Edward J., Zheng, Hui, Mukai, Chinatsu, Chu, Tinyi, Marks, Brooke A., Coonrod, Scott A., Danko, Charles G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882141/
https://ncbi.nlm.nih.gov/pubmed/29614078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194522
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