A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer

Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for endocrine resistance in breast cancer. We show that G...

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Udgivet i:PLoS One
Main Authors: Horibata, Sachi, Rice, Edward J., Zheng, Hui, Mukai, Chinatsu, Chu, Tinyi, Marks, Brooke A., Coonrod, Scott A., Danko, Charles G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882141/
https://ncbi.nlm.nih.gov/pubmed/29614078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194522
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