ER-positive breast cancer cells are poised for RET-mediated endocrine resistance

The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However, we know little about how ER+ cells activate RET signaling and initiate an endocrine resistant phenotype. Here we show that both ER+ endocrine resistant and sensitive breast can...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Horibata, Sachi, Rice, Edward J., Mukai, Chinatsu, Marks, Brooke A., Sams, Kelly, Zheng, Hui, Anguish, Lynne J., Coonrod, Scott A., Danko, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880349/
https://ncbi.nlm.nih.gov/pubmed/29608602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194023
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