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ER and PI3K independently modulate endocrine resistance in ER positive breast cancer
Endocrine Therapy Resistant Estrogen Receptor Positive (ER+) Breast Cancer is the most common cause of breast cancer death. Miller et al. demonstrate that ligand-independent ER activity promotes the growth of breast cancer cells through CDK4/E2F. As an independent event the PI3K pathway is also up r...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215586/ https://ncbi.nlm.nih.gov/pubmed/22096658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0192 |
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