Dynamic evolution of regulatory element ensembles in primate CD4+ T-cells

How evolutionary changes at enhancers affect the transcription of target genes remains an important open question. Previous comparative studies of gene expression have largely measured the abundance of mRNA, which is affected by post-transcriptional regulatory processes, hence limiting inferences ab...

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Detalhes bibliográficos
Publicado no:Nat Ecol Evol
Main Authors: Danko, Charles G., Choate, Lauren A., Marks, Brooke A., Rice, Edward J., Wang, Zhong, Chu, Tinyi, Martins, Andre L., Dukler, Noah, Coonrod, Scott A., Tait Wojno, Elia D., Lis, John T., Kraus, W. Lee, Siepel, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957490/
https://ncbi.nlm.nih.gov/pubmed/29379187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-017-0447-5
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