Dynamic evolution of regulatory element ensembles in primate CD4+ T-cells

How evolutionary changes at enhancers affect the transcription of target genes remains an important open question. Previous comparative studies of gene expression have largely measured the abundance of mRNA, which is affected by post-transcriptional regulatory processes, hence limiting inferences ab...

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Bibliografiska uppgifter
I publikationen:Nat Ecol Evol
Huvudupphovsmän: Danko, Charles G., Choate, Lauren A., Marks, Brooke A., Rice, Edward J., Wang, Zhong, Chu, Tinyi, Martins, Andre L., Dukler, Noah, Coonrod, Scott A., Tait Wojno, Elia D., Lis, John T., Kraus, W. Lee, Siepel, Adam
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957490/
https://ncbi.nlm.nih.gov/pubmed/29379187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-017-0447-5
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