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Paused Pol II captures enhancer activity and acts as a potent insulator

Enhancers act over many kilobase pairs to activate target promoters, but their activity is constrained by insulator elements that prevent indiscriminate activation of nearby genes. In the July 1, 2009, issue of Genes & Development, Chopra and colleagues (pp. 1505–1509) report that promoters cont...

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Détails bibliographiques
Auteurs principaux: Core, Leighton J., Lis, John T.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959990/
https://ncbi.nlm.nih.gov/pubmed/19605681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1827709
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