Advances in Neutrophil Biology: Clinical Implications

Por Cowburn, Andrew S., Condliffe, Alison M., Farahi, Neda, Summers, Charlotte, Chilvers, Edwin R.
Publicado em 2008

PI3Kδ and primary immunodeficiencies

Por Lucas, Carrie L., Chandra, Anita, Nejentsev, Sergey, Condliffe, Alison M., Okkenhaug, Klaus
Publicado no Nat Rev Immunol (2016)

Use of Technetium-99m–labeled Eosinophils to Detect Active Eosinophilic Inflammation in Humans

Por Farahi, Neda, Loutsios, Chrystalla, Peters, Adrien M., Condliffe, Alison M., Chilvers, Edwin R.
Publicado em 2013

Neutrophil kinetics in health and disease

Por Summers, Charlotte, Rankin, Sara M., Condliffe, Alison M., Singh, Nanak, Peters, A. Michael, Chilvers, Edwin R.
Publicado em 2010

Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells

Por Cowburn Andrew S, Rintoul Robert C, Walker Trevor R, Cadwallader Karen A, Condliffe Alison M, Chilvers Edwin R
Publicado em 2000-06-01

Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells

Por Condliffe, Alison M, Cadwallader, Karen A, Walker, Trevor R, Rintoul, Robert C, Cowburn, Andrew S, Chilvers, Edwin R
Publicado em 2000

Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human bone

Por Shead, Elizabeth F, Haworth, Charles S, Condliffe, Alison M, McKeon, Damian J, Scott, Mike A, Compston, Juliet E
Publicado em 2007

Incidence and recognition of acute respiratory distress syndrome in a UK intensive care unit

Por Summers, Charlotte, Singh, Nanak R, Worpole, Linda, Simmonds, Rosalind, Babar, Judith, Condliffe, Alison M, Gunning, Kevin E, Johnston, Andrew J, Chilvers, Edwin R
Publicado no Thorax (2016)

Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity

Por Walmsley, Sarah R., Print, Cristin, Farahi, Neda, Peyssonnaux, Carole, Johnson, Randall S., Cramer, Thorsten, Sobolewski, Anastasia, Condliffe, Alison M., Cowburn, Andrew S., Johnson, Nicola, Chilvers, Edwin R.
Publicado em 2005

Clinical application of autologous technetium-99m-labelled eosinophils to detect focal eosinophilic inflammation in the lung

Por Loutsios, Chrystalla, Farahi, Neda, Simmonds, Rosalind, Cullum, Ian, Gillett, Daniel, Solanki, Chandra, Solanki, Kishor, Buscombe, John, Condliffe, Alison M, Peters, A Mike, Chilvers, Edwin R
Publicado no Thorax (2015)

Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival

Por Juss, Jatinder K., Hayhoe, Richard P., Owen, Charles E., Bruce, Ian, Walmsley, Sarah R., Cowburn, Andrew S., Kulkarni, Suhasini, Boyle, Keith B., Stephens, Len, Hawkins, Phillip T., Chilvers, Edwin R., Condliffe, Alison M.
Publicado em 2012

Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition

Por Juss, Jatinder K., House, David, Amour, Augustin, Begg, Malcolm, Herre, Jurgen, Storisteanu, Daniel M. L., Hoenderdos, Kim, Bradley, Glyn, Lennon, Mark, Summers, Charlotte, Hessel, Edith M., Condliffe, Alison, Chilvers, Edwin R.
Publicado no Am J Respir Crit Care Med (2016)

Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

Por McGovern, Naomi N., Cowburn, Andrew S., Porter, Linsey, Walmsley, Sarah R., Summers, Charlotte, Thompson, Alfred A. R., Anwar, Sadia, Willcocks, Lisa C., Whyte, Moira K. B., Condliffe, Alison M., Chilvers, Edwin R.
Publicado no J Immunol (2010)

Hypoxia upregulates neutrophil degranulation and potential for tissue injury

Por Hoenderdos, Kim, Lodge, Katharine M, Hirst, Robert A, Chen, Cheng, Palazzo, Stefano G C, Emerenciana, Annette, Summers, Charlotte, Angyal, Adri, Porter, Linsey, Juss, Jatinder K, O'Callaghan, Christopher, Chilvers, Edwin R, Condliffe, Alison M
Publicado no Thorax (2016)

Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

Por Willcocks, Lisa C., Lyons, Paul A., Clatworthy, Menna R., Robinson, James I., Yang, Wanling, Newland, Stephen A., Plagnol, Vincent, McGovern, Naomi N., Condliffe, Alison M., Chilvers, Edwin R., Adu, Dwomoa, Jolly, Elaine C., Watts, Richard, Lau, Yu Lung, Morgan, Ann W., Nash, Gerard, Smith, Kenneth G.C.
Publicado em 2008

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

Por Thomas, David C., Clare, Simon, Sowerby, John M., Pardo, Mercedes, Juss, Jatinder K., Goulding, David A., van der Weyden, Louise, Storisteanu, Daniel, Prakash, Ananth, Espéli, Marion, Flint, Shaun, Lee, James C., Hoenderdos, Kim, Kane, Leanne, Harcourt, Katherine, Mukhopadhyay, Subhankar, Umrania, Yagnesh, Antrobus, Robin, Nathan, James A., Adams, David J., Bateman, Alex, Choudhary, Jyoti S., Lyons, Paul A., Condliffe, Alison M., Chilvers, Edwin R., Dougan, Gordon, Smith, Kenneth G.C.
Publicado no J Exp Med (2017)

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

Por Angulo, Ivan, Vadas, Oscar, Garçon, Fabien, Banham-Hall, Edward, Plagnol, Vincent, Leahy, Timothy R., Baxendale, Helen, Coulter, Tanya, Curtis, James, Wu, Changxin, Blake-Palmer, Katherine, Perisic, Olga, Smyth, Deborah, Maes, Mailis, Fiddler, Christine, Juss, Jatinder, Cilliers, Deirdre, Markelj, Gašper, Chandra, Anita, Farmer, George, Kielkowska, Anna, Clark, Jonathan, Kracker, Sven, Debré, Marianne, Picard, Capucine, Pellier, Isabelle, Jabado, Nada, Morris, James A., Barcenas-Morales, Gabriela, Fischer, Alain, Stephens, Len, Hawkins, Phillip, Barrett, Jeffrey C., Abinun, Mario, Clatworthy, Menna, Durandy, Anne, Doffinger, Rainer, Chilvers, Edwin, Cant, Andrew J., Kumararatne, Dinakantha, Okkenhaug, Klaus, Williams, Roger L., Condliffe, Alison, Nejentsev, Sergey
Publicado em 2013

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study

Por Coulter, Tanya I., Chandra, Anita, Bacon, Chris M., Babar, Judith, Curtis, James, Screaton, Nick, Goodlad, John R., Farmer, George, Steele, Cathal Laurence, Leahy, Timothy Ronan, Doffinger, Rainer, Baxendale, Helen, Bernatoniene, Jolanta, Edgar, J. David M., Longhurst, Hilary J., Ehl, Stephan, Speckmann, Carsten, Grimbacher, Bodo, Sediva, Anna, Milota, Tomas, Faust, Saul N., Williams, Anthony P., Hayman, Grant, Kucuk, Zeynep Yesim, Hague, Rosie, French, Paul, Brooker, Richard, Forsyth, Peter, Herriot, Richard, Cancrini, Caterina, Palma, Paolo, Ariganello, Paola, Conlon, Niall, Feighery, Conleth, Gavin, Patrick J., Jones, Alison, Imai, Kohsuke, Ibrahim, Mohammad A.A., Markelj, Gašper, Abinun, Mario, Rieux-Laucat, Frédéric, Latour, Sylvain, Pellier, Isabelle, Fischer, Alain, Touzot, Fabien, Casanova, Jean-Laurent, Durandy, Anne, Burns, Siobhan O., Savic, Sinisa, Kumararatne, D.S., Moshous, Despina, Kracker, Sven, Vanhaesebroeck, Bart, Okkenhaug, Klaus, Picard, Capucine, Nejentsev, Sergey, Condliffe, Alison M., Cant, Andrew James
Publicado no J Allergy Clin Immunol (2017)