Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

Neutrophils play a central role in the innate immune response and a critical role in bacterial killing. Most studies of neutrophil function have been conducted under conditions of ambient oxygen, but inflamed sites where neutrophils operate may be extremely hypoxic. Previous studies indicate that ne...

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Pubblicato in:J Immunol
Autori principali: McGovern, Naomi N., Cowburn, Andrew S., Porter, Linsey, Walmsley, Sarah R., Summers, Charlotte, Thompson, Alfred A. R., Anwar, Sadia, Willcocks, Lisa C., Whyte, Moira K. B., Condliffe, Alison M., Chilvers, Edwin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374781/
https://ncbi.nlm.nih.gov/pubmed/21135168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002213
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