Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

Neutrophils play a central role in the innate immune response and a critical role in bacterial killing. Most studies of neutrophil function have been conducted under conditions of ambient oxygen, but inflamed sites where neutrophils operate may be extremely hypoxic. Previous studies indicate that ne...

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Publicat a:J Immunol
Autors principals: McGovern, Naomi N., Cowburn, Andrew S., Porter, Linsey, Walmsley, Sarah R., Summers, Charlotte, Thompson, Alfred A. R., Anwar, Sadia, Willcocks, Lisa C., Whyte, Moira K. B., Condliffe, Alison M., Chilvers, Edwin R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374781/
https://ncbi.nlm.nih.gov/pubmed/21135168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002213
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