Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity

Neutrophils are key effector cells of the innate immune response and are required to migrate and function within adverse microenvironmental conditions. These inflammatory sites are characterized by low levels of oxygen and glucose and high levels of reductive metabolites. A major regulator of neutro...

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Autores principales: Walmsley, Sarah R., Print, Cristin, Farahi, Neda, Peyssonnaux, Carole, Johnson, Randall S., Cramer, Thorsten, Sobolewski, Anastasia, Condliffe, Alison M., Cowburn, Andrew S., Johnson, Nicola, Chilvers, Edwin R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212759/
https://ncbi.nlm.nih.gov/pubmed/15630139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040624
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