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Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
Iron is essential for many biological processes, including oxygen delivery, and its supply is tightly regulated. Hepcidin, a small peptide synthesized in the liver, is a key regulator of iron absorption and homeostasis in mammals. Hepcidin production is increased by iron overload and decreased by an...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884690/ https://ncbi.nlm.nih.gov/pubmed/17557118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31370 |
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