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TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
Hepcidin is an antimicrobial peptide secreted by the liver during inflammation that plays a central role in mammalian iron homeostasis. Here we demonstrate the endogenous expression of hepcidin by macrophages and neutrophils in vitro and in vivo. These myeloid cell types produced hepcidin in respons...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
© 2006 by The American Society of Hematology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895778/ https://ncbi.nlm.nih.gov/pubmed/16391018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2259 |
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