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Hepcidin Induction by Pathogens and Pathogen-Derived Molecules Is Strongly Dependent on Interleukin-6

Hepcidin, the iron-regulatory hormone, is increased during infection or inflammation, causing hypoferremia. This response is thought to be a host defense mechanism that restricts iron availability to invading pathogens. It is not known if hepcidin is differentially induced by bacterial versus viral...

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Библиографические подробности
Главные авторы: Rodriguez, Richard, Jung, Chun-Ling, Gabayan, Victoria, Deng, Jane C., Ganz, Tomas, Nemeth, Elizabeta, Bulut, Yonca
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911381/
https://ncbi.nlm.nih.gov/pubmed/24478088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00983-13
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