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GM-CSF CAUSES A PARADOXICAL INCREASE IN THE BH3-ONLY PRO-APOPTOTIC PROTEIN BIM IN HUMAN NEUTROPHILS

Neutrophil apoptosis is essential for the resolution of inflammation but delayed by several inflammatory mediators. In such terminally differentiated cells it has been uncertain whether these agents can inhibit apoptosis through transcriptional regulation of anti-death (Bcl-X(L), Mcl-1, Bcl2A1) or B...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Cowburn, Andrew S, Summers, Charlotte, Dunmore, Benjamin J, Farahi, Neda, Print, Cristin G, Cook, Simon J, Chilvers, Edwin R
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373550/
https://ncbi.nlm.nih.gov/pubmed/20705940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0101OC
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